Histo-epidemiological aspect of Helicobacter pylori chronic gastritis in a Moroccan population

Helicobacter pylori ( H. Pylori ) is the best example of implication chronical infection in carcinogenesis. The World Health Organization recognized it as a class I carcinogen since triggers progression premalignant gastric lesions. aim this study to define prevalence infection, related risk factors, and explore histological features chronic gastritis. This retrospective 248 specimens, examinated evaluated according Sydney system. 67 %, gastritis observed all biopsies (100%). Age gender were not factors for infection. Prevalence was 71.93% low socio-economic class. severity increases if colonization increases. In 74, 58% cases active. Glandular atrophy presented 10.37% 80% (p=0,004) 12 % autoimmune diseases. Intestinal metaplasia 10.53%, 42.31% (p=0.001). dysplasia detected one case, 72 years old patient. We also case adenocarcinoma, an 80 years. Follicular are 32% cases, they more frequent infected slides (82% subjects) (p< 0.005).According study, Chronic Gastritis very common our population, coherent relationship exists between pre-cancerous An early eradicating should be considered health goal.